B+ is a mono molecular layer of multi-phosphonates. It is permanently bound to the surface of the implant and is perceived as bone-like by the body.
The technology has been clinically demonstrated to result in visible bone growth directly on the surface of the B+ implant in sheep. The characteristics of B+ promote enhanced clinical performance and better preservation of bone levels around the implant as observed in a study with sheep. This may potentially lead to longer term implant survival, even in patients with compromised bone healing situations.
Molecules of B+ chemically bind to the implant surface, creating a hydrophilic surface and remain stable throughout the life span of the implant. The phosphonated molecules of B+ have demonstrated high stability in terms of chemical degradation. These properties prevent the molecules from detaching from the implant surface, which allows them to remain present for the lifespan of the implant.
This novel, phosphonate rich surface is designed to mimic one of the main constituents of bone, which may provide more favorable environment for implant integration. It has also been observed to accelerate the healing process, eliminate the “micro gap” between the bone and implant surface, and increase the fixation of the implant in bone.